The tainted weight loss products are:

Fatloss Slimming

2 Day Diet     

3x Slimming Power

Japan Lingzhi  24 Hours Diet

5x Imelda Perfect Slimming

3 Day Diet

7 Day Herbal Slim

8 Factor Diet

7 Diet Day/Night Formula

999 Fitness Essence

Extrim Plus

GMP

Imelda Perfect Slim

Lida DaiDaihua

Miaozi Slim Capsules

Perfect Slim

Perfect Slim 5x

Phyto Shape

ProSlim Plus

Royal Slimming Formula

Slim 3 in 1

Slim Express 360

Slimtech

Somotrim

Superslim

TripleSlim

Zhen de Shou

Venom Hyperdrive 3.0

An FDA analysis found that the undeclared active pharmaceutical ingredients in some of these products include sibutramine (a controlled substance), rimonabant (a drug not approved for marketing in the United States), phenytoin (an anti-seizure medication), and phenolphthalein (a solution used in chemical experiments and a suspected cancer causing agent). Some of the amounts of active pharmaceutical ingredients far exceeded the FDA-recommended levels, putting consumers’ health at risk.

These weight loss products, some of which are marketed as “dietary supplements,” are promoted and sold on various Web sites and in some retail stores. Some of the products claim to be “natural” or to contain only “herbal” ingredients, but actually contain potentially harmful ingredients not listed on the product labels or in promotional advertisements. These products have not been approved by the FDA, are illegal and may be potentially harmful to unsuspecting consumers. 

The FDA advises consumers who have used any of these products to stop taking them and consult their healthcare professional immediately. The FDA encourages consumers to seek guidance from a healthcare professional before purchasing weight loss products. 

“These tainted weight loss products pose a great risk to public health because they contain undeclared ingredients and, in some cases, contain prescription drugs in amounts that greatly exceed their maximum recommended dosages,” said Janet Woodcock, M.D., director, Center for Drug Evaluation and Research, FDA. “Consumers have no way of knowing that these products contain powerful drugs that could cause serious health consequences. Therefore FDA is taking this action to protect the health of the American public.”

The FDA has inspected a number of companies associated with the sale of these illegal products, and is currently seeking product recalls. Based on the FDA’s inspections and the companies’ inadequate responses to recall requests, the FDA may take additional enforcement steps, such as issuing warning letters or initiating seizures, injunctions, or criminal charges.

The health risks posed by these products can be serious; for example, sibutramine, which was found in many of the products, can cause high blood pressure, seizures, tachycardia, palpitations, heart attack or stroke. This drug can also interact with other medications that patients may be taking and increase their risk of adverse drug events. The safety of sibutramine has also not been established in pregnant and lactating women, or in children younger than 16 years of age.

Rimonabant, another ingredient found in these products, was evaluated, but not approved by the FDA for marketing in the United States. The drug, which is approved in Europe, has been associated with increased risk of depression and suicidal thoughts and has been linked to five deaths and 720 adverse reactions in Europe over the last two years.
Health care professionals and consumers should report serious adverse events (side effects) or product quality problems to the FDA’s MedWatch Adverse Event Reporting program either online, by regular mail, fax or phone.

• Online: www.fda.gov/MedWatch/report.htm
• Regular Mail: use postage-paid FDA form 3500 available at: www.fda.gov/MedWatch/getforms.htm and mail to MedWatch, 5600 Fishers Lane, Rockville, MD 20852-9787
• Fax: (800) FDA-0178
• Phone: (800) FDA-1088

Information for consumers can be found at:
http://www.fda.gov/cder/consumerinfo/weight_loss_products.htm

To learn more about FDA’s initiative against unapproved drugs read FDA’s Compliance Policy Guide here: http://www.fda.gov/cder/Guidance/6911fnl.htm.

For drug safety information, read: FDA’s Drug Safety Initiative

New research backs up the long-held claim, and shows that drivers make more mistakes chatting away on cell phones than when talking to a passenger in the seat next to them.

In the December issue of the Journal of Experimental Psychology: Applied, published by the American Psychological Association, a study finds drivers on cell phones are more likely to drift from their lane, miss their exit, and make other dangerous mistakes.

Drivers using a hands-free cell phone also found their performance at the wheel was significantly compromised. "Cell phone and passenger conversation differ in their impact on a driver’s performance; these differences are apparent at the operational, tactical, and strategic levels of performance," the researchers wrote.

Image above caption: University of Utah psychology graduate students Russ Costa and Janelle Seegmiller demonstrate the driver and passenger roles used by participants in a study of how drivers are affected by conversations with passengers versus conversations over a cell phone. The study, which used the sophisticated driving simulator shown in the photo, found that when drivers talk on cell phones, they are more likely to drift out of their lane and miss exits.
Photo Credit: Nate Medeiros-Ward

Frank Drews, PhD, of the University of Utah, led the study which analyzed the driving performance of 41 mostly young adult drivers paired with 41 friends who served as conversation partners. Both sexes were equally represented.

The study used three experimental conditions (conversation with hands-free cell phone, conversation in the car, or no conversation). One person in each pair was randomly selected to be the "driver" and the other the conversation partner.

A sophisticated simulator that presented a 24-mile multilane highway with on- and off-ramps, overpasses and two-lane traffic in each direction put the drivers to the 10-minute test. They drove under an irregular-flow condition that mimics real highway conditions — with other vehicles, in compliance with traffic laws, changing lanes and speeds. This context required "drivers" to pay attention to surrounding traffic.

In the cell-phone conversation test, conversation partners were at another location. In the in-car conversation option, partners sat next to drivers. All drivers were told to exit the simulated highway once they arrived at a rest area about eight miles from the starting point.

Drivers talking on cell phones drove significantly worse than drivers talking to passengers. The cell-phone users drifted more in their lane, kept a greater distance between their car and the car in front of them, and were four times more likely to miss the instructed rest area exit. Passenger conversation insignificantly affected all three testing options.

Since the early 1990s, more than 20 species of Bartonella bacteria have been discovered. They are considered to be emerging zoonotic pathogens, because they can cause serious illness in humans worldwide from heart disease to infection of the spleen and nervous system.

"A new species called Bartonella rochalimae was recently discovered in a patient with an enlarged spleen who had travelled to South America," said Professor Chao-Chin Chang from the National Chung Hsing University in Taiwan. "This event raised concern that it could be a newly emerged zoonotic pathogen. Therefore, we decided to investigate further to understand if rodents living close to human environment could carry this bacteria."

Scientists have found that rodents carry several pathogenic species of Bartonella, such as B. elizabethae, which can cause endocarditis and B. grahamii, which was found to cause neuroretinitis in humans. Although scientists are unsure about the main route of transmission, these infections are most likely to be spread by fleas. Ctenophthalmus nobilis, a flea that lives on bank voles, was shown to transmit different species of Bartonella bacteria. These pathogens have also been found in fleas that live on gerbils, cotton rats and brown rats.

"We analysed bacteria found in Rattus norvegicus in Taiwan. The brown rat is also the most common rat in Europe," said Professor Chang. "By analysing the DNA of the bacteria, we discovered a strain that is most closely related to B. rochalimae, which has been isolated recently from a human infection in the United States".

The researchers took samples from 58 rodents, including 53 brown rats, 2 mice (Mus musculus) and 3 black rats (Rattus rattus). 6 of the rodents were found to be carrying Bartonella bacteria; 5 of these were brown rats. Four of the rodents were carrying B. elizabethae, which can cause heart disease in humans, and one of the black rats was found to be harbouring B. tribocorum. However, the scientists noticed one strain that had not been identified in rodents previously. The strain was finally shown to be close to B. rochalimae.

"Because of the small sample size used in this study, we cannot say for sure that the common brown rat is spreading B. rochalimae," said Professor Chang. "However, several different Bartonella bacteria are surely transmitted by rodents. These results raise concerns about the existence of other reservoirs and vectors for this emerging infection. This certainly warrants further investigation."

Source: Society for General Microbiology

The proportion of working-age Americans who have medical bill problems or who are paying off medical debt climbed from 34 percent to 41 percent between 2005 and 2007, bringing the total to 72 million, according to recent survey findings from The Commonwealth Fund. In addition, 7 million adults age 65 and over also had problems paying medical bills, for a total of 79 million adults with medical bill problems or medical debt.

In a new Commonwealth Fund report about the survey findings, Losing Ground: How the Loss of Adequate Health Insurance is Burdening Working Families, the authors describe how working-age adults are becoming more exposed to the rising costs of health care, either because they have lost insurance through their jobs or because they are paying more out of pocket for their health care. This combination of factors, along with sluggish growth in average family incomes, is contributing to problems with medical bills and cost-related delays in getting needed health care.

The report finds that in 2007, nearly two-thirds of U.S. adults under age 65, or 116 million people, had medical bill problems or debt, went without needed care because of cost, were uninsured for a time, or were underinsured—insured but had high out-of-pocket medical expenses or deductibles relative to income.

“We are seeing a perfect storm of negative economic trends threatening working families in the United States,” said Sara Collins, Commonwealth Fund Assistant Vice President, and the study’s lead author. “While gas and food prices are increasing and home values are declining, the rise in health care costs is surpassing income growth and fewer people have adequate insurance. As a result, working people are struggling to pay their bills and accruing medical debt.”

While the increase in problems paying medical bills or carrying unpaid medical bills cuts across income brackets, low and moderate income families are burdened the most. The report finds that more than half of working-age adults earning less than $40,000 a year reported problems paying medical bills or being in debt due to medical expenses. Medical bill problems included not being able to pay bills, being contacted by a collection agency about an unpaid bill, and changing one’s way of life in order to pay medical bills.

Those with medical bills and medical debt are increasingly facing serious financial problems and sometimes facing trade-offs among immediate life necessities. Thirty-nine percent of those with bill problems or debt say they have used up all of their savings to pay their health care bills; 29 percent are unable to pay for basic necessities like food, heat, or rent; and 30 percent took on credit card debt. Twenty-four percent of adults under age 65 with medical debt owe $4,000 or more and 12 percent owe $8,000 or more in unpaid medical expenses.

In a new Commonwealth Fund issue brief which accompanies the report, Seeing Red: The Growing Problem of Medical Debt and Bills, the authors explain that uninsured and underinsured adults are more at risk of having medical bill problems and medical debt than those with adequate insurance coverage. Three in five adults who are uninsured or underinsured face these challenges, more than double the rate of those who had adequate insurance all year (26 percent). Notably, adults 65 years and older were far less likely to report medical bill problems or debt than younger adults because they are covered by Medicare and may also have supplemental private coverage, and in the case of low-income individuals, may have Medicaid. Just 19 percent of adults over 65—half the rate for adults under 65 (41%)—reported any medical bill problems or debt.

“The current economic slowdown makes it even more urgent for a new Administration to make universal and affordable health insurance a high priority in 2009, to ensure that no American suffers financial hardship as a result of serious illness,” said Commonwealth Fund President Karen Davis.

The report also finds that more working-age adults are delaying or avoiding needed medical care, such as skipping doses of medication or not filling prescriptions, because of health care costs. Forty-five percent of adults reported problems getting care because of costs in 2007, a dramatic increase from 29 percent in 2001. Increasing numbers of adults are spending high proportions of their income on health care. One-third of U.S. working-age adults spent 10 percent or more of their income on out-of-pocket medical expenses and health insurance premiums in 2007, up from 21 percent in 2001.

The proportion of Americans who are uninsured continues to grow. More than one-quarter (28%) of U.S. adults ages 19 to 64, or an estimated 50 million people, were uninsured for some time in 2007, compared with 24 percent in 2001. But even having insurance coverage does not guarantee protection from medical bill problems and debt. The proportion of those who are underinsured increased from 9 percent to 14 percent, or 25 million people, between 2003 and 2007. Sixty-one percent of those with medical bill problems or accumulated medical debt were insured at the time care was provided.

Other key survey findings include:

- Among the medical bill problems reported in the survey: 28 percent are paying off medical bills over time, up from 21 percent in 2005, and 27 percent of adults under age 65 said they had problems paying or were unable to pay their bills in 2007, up from 23 percent in 2005.

- More than half (53%) of insured working-age adults who have deductibles that represent 5 percent or more of their income reported medical bill burdens and debt; one-third of adults with lower deductibles face these kinds of difficulties.

- While adults in families with incomes under $20,000 a year report the highest rates of lacking coverage during the year, more adults in moderate income families are going without insurance. In 2007, 41 percent of adults in families earning between $20,000 and $40,000 a year reported a time uninsured during the year, up from 28 percent in 2001.

- Most people who were uninsured at any point in the last year are in working families. Of the estimated 50 million American adults who were uninsured in the last year, 58% were in families where at least one person was working full-time.

- People who are uninsured or underinsured experience inefficient care; nearly half of adults (47%) under age 65 who had gaps in their health insurance or were underinsured reported they had experienced problems such as test results not being available on time, receiving duplicate medical tests, and delays in receiving results of abnormal test results; in contrast just 26 percent of adults who are adequately insured reported these inefficiencies.

Source: Commonwealth Fund.

The flu bug is the target of new seasonal vaccines announced today by the U.S. Food and Drug Administration.

The influenza vaccines include new strains of the virus likely to appear during the 2008-2009 season. The strains were identified in a group effort with the FDA, the World Health Organization, U.S. Centers for Disease Control and Prevention, and other institutions after study of virus samples and patterns collected around the globe during the last year.

“One of the biggest challenges in the fight against influenza is producing new vaccines every year,” said Jesse L. Goodman, M.D., M.P.H., director of FDA’s Center for Biologics Evaluation and Research. “There is no other instance where new vaccines must be made every year. The approval of flu vaccines is a part of FDA’s mission to promote the health of Americans throughout the year.”

While many Americans reported getting the flu last year, even after receiving a flu shot, experts say vaccination remains the cornerstone of preventing the contagious respiratory illness caused by influenza viruses.

The CDC says an average of 5 to 20 percent of the U.S. population gets the flu annually. Of those, more than 200,000 are hospitalized from flu complications and there are about 36,000 flu-related deaths.

“People have a hard time adhering to diets and our research shows that choosing eggs for breakfast can dramatically improve the success of a weight loss plan,” said Nikhil V. Dhurandhar, Ph.D., lead researcher and associate professor in the laboratory of infection and obesity at Pennington Biomedical Research Center, a campus of the Louisiana State University system. “Apparently, the increased satiety and energy due to eggs helps people better comply with a reduced-calorie diet.”

Significant Weight Loss Related to Egg Breakfast

Compared to the subjects who ate a bagel breakfast, men and women who consumed two eggs for breakfast as part of a reduced-calorie diet:

* lost 65 percent more weight
* exhibited a 61 percent greater reduction in BMI
* reported higher energy levels than their dieting counterparts who consumed a bagel breakfast [1]

The egg and bagel breakfasts provided the same number of calories and had identical weights (energy density), which is an important control factor in satiety and weight loss studies.

The researchers also found that blood lipids were not impacted during the two month study. They found that blood levels of HDL and LDL cholesterol, as well as triglycerides, did not vary compared to baseline cholesterol blood levels in subjects who ate either the bagel or egg breakfasts. These findings add to more than 30 years of research that conclude that healthy adults can enjoy eggs without significantly impacting their risk of heart disease.

New Emphasis on the Importance of High-Quality Protein

This study adds to the growing body of research which supports the importance of high-quality protein in the diet. The American Journal of Clinical Nutrition (AJCN) published a special issue in May 2008, which contains nine articles that focus on the value of high-quality protein in the American diet. A major finding was that not getting enough high-quality protein may contribute to obesity, muscle wasting (loss) and increased risk of chronic disease.

Jump Start the Morning with Eggs

Jackie Newgent, registered dietitian and chef, stresses the importance of obtaining adequate high-quality protein when advising consumers about weight loss. “Eggs are a good source of all-natural, high-quality protein, so they can help keep you satisfied longer, making it easier to resist tempting snacks,” said Newgent. “Nearly half of an egg’s protein, and many of the other nutrients, are found in the yolk, so make sure to eat the whole egg for maximum benefits.”

Newgent suggests these nutrition tips for a successful weight loss plan:

- Manic Monday: Make a batch of hard-cooked eggs on Sunday, so you’ll have all-natural, high-quality protein meals for your on-the-go schedule during the week. Plus, eggs are incredibly affordable. At an average of $1.93 per dozen (or $0.16 per egg), [5] eggs are one of the most affordable high-quality protein foods in the marketplace.

- In-a-Minute Morning Meal: In less than 60 seconds, you can prepare an egg breakfast to help jump start your day. Simply beat one whole egg in a microwave-safe mug then cook in the microwave oven on high for 60 seconds. Slide the egg onto a whole grain English muffin. Add flavor with a sprinkling of fresh herbs, salsa, or cheese. Serve fresh seasonal fruit slices, like peaches in the summer, on the side for a balanced meal.

Source: Edelman Public Relations.

That’s because scientists say watermelon has ingredients that deliver Viagra-like effects to the body’s blood vessels and may even increase libido.

“The more we study watermelons, the more we realize just how amazing a fruit it is in providing natural enhancers to the human body,” said Dr. Bhimu Patil, director of Texas A&M’s Fruit and Vegetable Improvement Center in College Station.

“We’ve always known that watermelon is good for you, but the list of its very important healthful benefits grows longer with each study.”

Beneficial ingredients in watermelon and other fruits and vegetables are known as phyto-nutrients, naturally occurring compounds that are bioactive, or able to react with the human body to trigger healthy reactions, Patil said.

In watermelons, these include lycopene, beta carotene and the rising star among its phyto-nutrients – citrulline – whose beneficial functions are now being unraveled. Among them is the ability to relax blood vessels, much like Viagra does.

Scientists know that when watermelon is consumed, citrulline is converted to arginine through certain enzymes. Arginine is an amino acid that works wonders on the heart and circulation system and maintains a good immune system, Patil said.

“The citrulline-arginine relationship helps heart health, the immune system and may prove to be very helpful for those who suffer from obesity and type 2 diabetes,” said Patil. “Arginine boosts nitric oxide, which relaxes blood vessels, the same basic effect that Viagra has, to treat erectile dysfunction and maybe even prevent it.”

While there are many psychological and physiological problems that can cause impotence, extra nitric oxide could help those who need increased blood flow, which would also help treat angina, high blood pressure and other cardiovascular problems.

“Watermelon may not be as organ specific as Viagra,” Patil said, “but it’s a great way to relax blood vessels without any drug side-effects.”

The benefits of watermelon don’t end there, he said. Arginine also helps the urea cycle by removing ammonia and other toxic compounds from our bodies.

Citrulline, the precursor to arginine, is found in higher concentrations in the rind of watermelons than the flesh. As the rind is not commonly eaten, two of Patil’s fellow scientists, drs. Steve King and Hae Jeen Bang, are working to breed new varieties with higher concentrations in the flesh.

In addition to the research by Texas A&M, watermelon’s phyto-nutrients are being studied by the U.S. Department of Agriculture’s Agricultural Research Service in Lane, Oklahoma.

As an added bonus, these studies have also shown that deep red varieties of watermelon have displaced the tomato as the lycopene king, Patil said. Almost 92 percent of watermelon is water, but the remaining 8 percent is loaded with lycopene, an anti-oxidant that protects the human heart, prostate and skin health.

“Lycopene, which is also found in red grapefruit, was historically thought to exist only in tomatoes,” he said. “But now we know that it’s found in higher concentrations in red watermelon varieties.”

Lycopene, however, is fat-soluble, meaning that it needs certain fats in the blood for better absorption by the body, Patil said.

“Previous tests have shown that lycopene is much better absorbed from tomatoes when mixed in a salad with oily vegetables like avocado or spinach,” Patil said. “That would also apply to the lycopene from watermelon, but I realize mixing watermelon with spinach or avocadoes is a very hard sell.”

No studies have been conducted to determine the timing of the consumption of oily vegetables to improve lycopene absorption, he said.

“One final bit of advice for those Fourth of July watermelons you buy,” Patil said. “They store much better uncut if you leave them at room temperature. Lycopene levels can be maintained even as it sits on your kitchen floor. But once you cut it, refrigerate. And enjoy.”

Source: Texas A&M University

In the flood-ravaged midwest, health officials are concerned that standing water could provide the perfect breeding ground for scores of mosquitoes.

The Centers for Disease Control says so far this year, eight human cases have been reported in five states (Arizona, Mississippi, Oklahoma, Tennessee and Texas), and animal cases in nine states (Alabama, California, Florida, Illinois, Indiana, Louisiana, South Carolina, Texas and Utah).

Last year, there were 2,630 human cases of West Nile reported in the United States. Health officials have been tracking West Nile since the disease first showed up in New York in 1999.

The CDC advises people to protect against mosquito bites with the following tips:

• Use Mosquito Repellent
• Eliminate standing water where mosquitoes can lay eggs
• Install or Repair Window and Door Screens
• Support Community-Based Mosquito Control Programs

Photo above courtesy of the Illinois Department of Public Health website.

The study represents a collaboration between researchers at the University of Maryland, Stanford University, and École Supérieure d’Électricité (Gif-sur-Yvette, France).

“By combining novel biological data and mathematical modeling, we found rules for designing adaptive treatments for each specific patient,” said Professor Doron Levy. “Give me a thousand patients and, with this mathematical model, I can give you a thousand different customized treatment plans.”

The study by Levy, Professor Peter P. Lee and Dr. Peter S. Kim uses data collected over four years from CML patients during imatinib therapy.

“Our results suggest that it is not only the drug that sends the leukemia into remission, it’s also the natural immune response,” Levy said. “After starting imatinib, the anti-leukemia immune response gradually increases. However, it begins to weaken after it reaches a peak [as the leukemia cells are greatly diminished in number]. This typically happens well into the treatment.”

This provides a window for cancer cells to develop drug resistance that could render the therapy ineffective. The authors therefore recommend strengthening the immune system at this, its weakest point through “cancer vaccines” in which pre-therapy blood taken from patients is irradiated to kill active cancer cells and then introduced back to the patient.

Levy and Lee are currently conducting further studies to expand on the results of this research, which they hope will lead to the development of animal models and, eventually, clinical trials.

Source: Public Library of Science.

that’s why a consumer group is urging retailers to stop selling PVC shower curtains.

The Center for Health, Environment & Justice has just published “Volatile Vinyl: The New Shower Curtain’s Chemical Smell”, which claims more than 100 chemicals are released into the air when consumers open the packages containing the curtains. The CHEJ is also calling on the Consumer Product Safety Commission to recall the curtains from store shelves.

The CHEJ says it discovered the hazards in a study of shower curtains made with polyvinyl chloride (PVC) plastic. The curtains reportedly contain many harmful chemicals including volatile organic compounds (VOCs), phthalates and organotins. The study found that exposure to the chemicals creates health problems such as respiratory irritation, central nervous system, liver and kidney damage, nausea, headaches and loss of coordination.

The CHEJ purchased PVC shower curtains at Bed Bath & Beyond, Kmart, Sears, Target and Wal-Mart to be used as samples for the testing.

For more information: www.chej.org/showercurtainreport